Recent advancements in additive manufacturing are poised to revolutionize the construction sector, particularly through the innovative application of stereolithography (SLA) in bioprinting. A new study led by Shu-Yung Chang from the Pillar of Engineering Product Development at the Singapore University of Technology and Design explores the potential of poly(ethylene‐glycol)‐dimethacrylate (PEGDMA) as a bioink supplement, offering a more accessible alternative to traditional high molecular weight poly(ethylene‐glycol)‐diacrylate (PEGDA).
The significance of this research cannot be overstated. In the realm of bioprinting, the ability to create complex, biomimetic structures is essential for applications ranging from tissue engineering to regenerative medicine. The study demonstrates that PEGDMA, with a molecular weight of 1000 Da, can enhance the mechanical properties of SLA-printed constructs, making it a compelling choice for laboratories that may not have the resources to synthesize high molecular weight PEGDA in-house.
“By using PEGDMA, we can simplify the bioink formulation process, allowing more labs to participate in the exciting field of bioprinting,” Chang stated. This democratization of technology could lead to a surge in the development of intricate bioinspired structures, which could find applications in various sectors, including construction. Imagine 3D-printed building materials that not only mimic natural forms but also integrate biological functions, enhancing sustainability and efficiency.
The research highlights the successful fabrication of 3D constructs featuring overhangs and complex architectures, which is a significant milestone for the industry. Furthermore, the cytocompatibility of the GelMA-PEGDMA bioink, demonstrated by a cell viability rate of 71–87% over six days, underscores its potential for creating viable cell-laden structures. This capability could pave the way for constructing living materials that adapt to their environments, a concept that could reshape how buildings interact with their surroundings.
As the construction industry increasingly turns to innovative materials and techniques, the findings from this study published in ‘Macromolecular Materials and Engineering’ (translated as ‘Macromolecular Materials and Engineering’) could serve as a catalyst for future developments. The accessibility of PEGDMA may not only facilitate advancements in 3D bioprinting but also inspire new architectural designs that integrate biological elements, creating structures that are not only functional but also harmoniously aligned with nature.
For those interested in exploring this research further, more information can be found at lead_author_affiliation. The implications of this work extend beyond the lab, promising to influence how we think about and approach construction in the years to come.
