Recent research published in ‘Applied Surface Science Advances’ sheds light on a promising advancement in the realm of bioresorbable polymeric stents, a critical component in the treatment of atherosclerosis. Conducted by Ana M. Sousa and her team from the University of Coimbra, this study delves into optimising metallic coatings to enhance the mechanical and surface performance of these stents, which are vital for cardiovascular health.
Atherosclerosis remains a significant global health issue, and while coronary stents have been instrumental in treatment, challenges such as cellular compatibility and mechanical strength continue to impede their efficacy. Polymeric Bioresorbable Stents (BRS) have emerged as a potential solution, yet their performance can be significantly improved. Sousa’s research explores the application of biodegradable metallic coatings, specifically magnesium (Mg) and zinc (Zn), deposited through non-reactive radiofrequency magnetron sputtering. This innovative approach aims to marry the benefits of bioresorbable polymers with the mechanical robustness of metal.
“The findings suggest that while Mg coatings can provide certain advantages, such as reduced thrombus formation, it is the Zn coatings—especially those produced at 0.4 Pa—that stand out in terms of mechanical properties and safety,” Sousa explained. This nuanced understanding of the interplay between coating thickness, mechanical performance, and degradation rates is critical for the future design of stents that can better serve patients.
The implications of this research extend beyond the medical field and into the construction sector, particularly in the development of medical devices and implants. With the global market for cardiovascular devices projected to grow significantly, advancements in stent technology could lead to reduced healthcare costs and improved patient outcomes, ultimately influencing the construction of medical facilities and manufacturing processes. Enhanced stent designs could also pave the way for more innovative applications of bioresorbable materials in various construction contexts, including temporary supports or scaffolding in medical settings.
Sousa’s work not only provides a pathway for better stents but also opens up discussions about the broader applications of biodegradable materials in construction and engineering. As the industry moves towards more sustainable practices, the insights gained from this study could inspire new methodologies and materials that align with environmental goals.
As Sousa and her team continue to refine their findings, the construction sector stands to benefit from these advancements in stent technology, potentially revolutionising how medical devices are integrated into health infrastructure. For more information on this research and its implications, you can visit the Department of Mechanical Engineering at the University of Coimbra.