Recent advancements in material science have unveiled a groundbreaking approach to drug delivery systems that could have significant implications for the construction sector, particularly in the development of smart materials. Researchers led by Sharanappa Chapi from the Department of Physics at B.M.S. College of Engineering in Bengaluru have synthesized a novel tragacanth gum-based hydrogel that incorporates silver nanoparticles, offering both sustained drug release and antibacterial properties.
This innovative hydrogel, known as TG-g-PAMPS, is created through a process called free radical copolymerization, which utilizes microwave radiation to form a cross-linked network. The incorporation of silver nanoparticles not only enhances the swelling capacity of the hydrogel but also imparts antibacterial characteristics, making it a potential game-changer for construction materials that require durability and hygiene.
Chapi emphasizes the dual benefits of this material, stating, “The TG-g-PAMPS gel not only serves as an effective drug delivery system but also provides significant antibacterial properties, which can be crucial in environments where microbial growth poses a risk.” This is particularly relevant in the construction industry, where materials that can resist microbial contamination could lead to safer and more sustainable building practices.
The study reveals that the hydrogel can effectively release diclofenac sodium, a common anti-inflammatory drug, in a controlled manner. This controlled release was found to follow the Korsmeyer–Peppas model, indicating a sophisticated mechanism that could be tailored for specific applications. The implications for construction are profound; imagine integrating such smart materials into building designs, where they could actively respond to environmental conditions or even deliver therapeutic agents in healthcare facilities.
Additionally, the antibacterial properties of the TG-g-PAMPS gel against common pathogens like Pseudomonas aeruginosa and Escherichia coli could lead to the development of construction materials that maintain hygiene over time, reducing the need for frequent maintenance or chemical treatments. This could result in significant cost savings and enhanced safety in public infrastructure.
As this research continues to evolve, the potential applications in construction and beyond are vast. With materials that not only perform but also protect against microbial threats, the industry could see a shift towards smarter, more resilient structures. The findings of this study were published in ‘Nano Select,’ which translates to “Nano Selection,” highlighting the meticulous process of selecting high-quality materials for advanced applications.
For more information on this pioneering research, you can visit B.M.S. College of Engineering.
