Recent advancements in biosensing technology have taken a significant leap forward with the development of a high-performance photonic crystal fibre (PCF) biosensor, specifically designed to detect Jurkat cells—immortalized human T lymphocyte cells pivotal in leukemia research. This innovative sensor, crafted by a team led by Most. Momtahina Bani from the Department of Electrical and Electronic Engineering at Pabna University of Science and Technology in Bangladesh, could revolutionize both biomedical research and clinical diagnostics.
Jurkat cells are known for their aggressive nature, serving as essential models in understanding leukemia and the immune response. The new PCF biosensor demonstrates remarkable sensitivity, achieving a maximum relative sensitivity of 95.81% for Jurkat type I cells and 94.93% for type II. This high sensitivity to refractive index changes allows for label-free and real-time monitoring of cell interactions, a feature that could significantly enhance research capabilities in oncology and immunology.
“The ability to detect Jurkat cells with such precision opens up new avenues for research and potential therapies,” said Bani. “Our sensor’s design facilitates high light-matter interaction and offers custom geometry, making it not only effective but also biocompatible for specific applications.”
For the construction sector, the implications of this technology could be profound. As the demand for advanced biotechnological applications grows, construction firms involved in building laboratories and research facilities may find new opportunities in integrating such cutting-edge technologies into their projects. The potential for creating specialized environments that support high-precision biosensing could lead to increased investments in biomedical infrastructure.
Moreover, the commercial viability of this PCF sensor could pave the way for more widespread use in diagnostic tools and therapeutic monitoring, ultimately enhancing patient outcomes in healthcare settings. The ability to monitor cellular interactions in real time can lead to faster diagnosis and more effective treatment plans, which is a critical need in the rapidly evolving landscape of medical science.
The findings were published in ‘IET Nanodielectrics,’ a journal that focuses on the latest research in nanostructured materials and their applications. As the construction industry increasingly intersects with biomedicine, advancements like these will play a crucial role in shaping future developments, emphasizing the need for collaboration between engineers, biologists, and healthcare professionals.
For further information on this research and its implications, you can visit Pabna University of Science and Technology.
