Turkish Researchers Craft Antimicrobial Nanofibers for Wound Healing

In a significant stride towards advancing antimicrobial and biocompatible materials, researchers have developed a novel composite nanofiber that could revolutionize wound dressings and tissue engineering. The study, led by Nilüfer Evcimen Duygulu from the Faculty of Chemical and Metallurgical Engineering at Yildiz Technical University in Istanbul, Turkey, introduces hexagonal boron nitride (h-BN) doped polyvinyl alcohol (PVA) composite nanofibers, offering a cost-effective and straightforward solution with profound implications for the biomedical and energy sectors.

The research, published in *Macromolecular Materials and Engineering* (translated from German as “Macromolecular Materials and Engineering”), details the fabrication of these composite nanofibers using the electrospinning technique. The resulting fibers, with an average diameter of approximately 376 nanometers, exhibited remarkable properties. “The uniform dispersion of boron nitride nanoparticles within the PVA matrix was crucial for enhancing the material’s performance,” Duygulu explained.

One of the standout findings was the enhanced antimicrobial activity of the PVA/BN composite nanofibers. The fibers demonstrated significant inhibition zones against Escherichia coli, Staphylococcus aureus, and Candida albicans, with an impressive inhibition rate of 89.56% against E. coli. This antimicrobial prowess, coupled with the material’s excellent biocompatibility—exceeding 98% cell viability—positions it as a promising candidate for advanced wound dressings and tissue engineering applications.

The study also highlighted the hydrophobic nature of the boron nitride nanoparticles, which dominated the water absorption tests. This property could be particularly beneficial in applications requiring moisture resistance, such as in certain energy storage devices or protective coatings.

The commercial impacts of this research are substantial. In the biomedical sector, the development of antimicrobial and biocompatible materials is a persistent challenge. The PVA/BN composite nanofibers offer a viable solution, potentially reducing infection rates and improving patient outcomes. Moreover, the enhanced structural stability and unique functional groups identified through Fourier transform infrared spectroscopy (FT-IR) suggest that these materials could be tailored for specific applications, opening new avenues for innovation.

In the energy sector, the hydrophobic nature of the composite nanofibers could lead to advancements in battery technology and other energy storage systems. The ability to control moisture absorption is critical for the longevity and efficiency of these devices, and the PVA/BN composite nanofibers could play a pivotal role in this regard.

As the world continues to seek sustainable and efficient materials for various applications, the PVA/BN composite nanofibers represent a significant step forward. The research conducted by Duygulu and her team not only addresses current challenges but also paves the way for future developments in the field of advanced materials. The study’s findings, published in *Macromolecular Materials and Engineering*, underscore the importance of interdisciplinary research in driving innovation and shaping the future of technology.

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